The Ozark Foothills Regional Planning Commission assists in the promotion of the economic growth of five counties in Southeast Missouri:
Nestled within these counties are 16 municipalities: Bunker, Centerville, Doniphan, Ellington, Ellsinore, Fisk, Grandin, Greenville, Mill Spring, Naylor, Neelyville, Piedmont, Poplar Bluff, Qulin, Van Buren, and Williamsville. The region boasts seven industrial parks.
The five-county region is midway between St. Louis, MO, Memphis, TN, and Little Rock, AR. St. Louis lies 160 miles northeast, with Memphis 160 miles to the south.
The Ozark Foothills Region has 83,376 residents, a 34.8 percent increase from the 61,862 counted in the 1970 census. Making up this total are Butler County, with 42,794 residents, an increase of 27.6 percent over 1970's census; Carter County, 5,941, up 61.5 percent; Reynolds County, 6,696, up 9.7 percent; Ripley County, 14,100, an increase of 43.8 percent; and Wayne County, with 13,521 residents, up 58.2 percent from 1970. The median family income in 2010 for the Ozark Foothills Region was $19,895.
The climate in the rolling hills of the five-county area averages 70.5 degrees. In January, the average temperature is 31.4 degrees, with the hottest month, July, seeing 91.8 degrees. The area measured an average annual rainfall of 37.26 inches and average snowfall of just over nine inches.