• Class: 3
• County Seat: Doniphan
• Pop: 10,679 (2020)
• Value: $104,839,054 (2021)
• Sq Mi: 632
• Presiding Commissioner: Jesse Roy, Jr., Courthouse located at 101 Courthouse Square in Doniphan
• Major Employers: Vitronic, Current River Nursing Center, Missouri Forge, Public School Systems
• Education: 6 public systems, 3 private systems
• Healthcare: Naylor Clinic, Ripley County Family Clinic, Good Samaritan Clinic, Doniphan Medical Clinic
• Transportation: 18 miles to US Hwy 67, 85 miles to I-55 | US 160 | MO 21, 142 | Co J, C, Y, NN, K, BB, M, JJ, T, B, AA, Z, P, DD, EE, CC, FF, A, U, E, N, H, W
• Airports: Doniphan Municipal Airport, Public - Poplar Bluff - 35 miles, Commercial - Cape Girardeau - 102 miles
• Recreation: Mark Twain National Forest, Current River

Ripley County, with a population of 10,679, is located in the southwestern portion of the Ozark Foothills Region. Some major industries and employers in the county include Vitronic, Current River Nursing Center, Missouri Forge, the sawmill industry, the agricultural sector, and the public school systems. Three clinics offer high-quality medical assistance to county residents, while three private systems and six public school systems educate children living in the county. A variety of recreational areas, including Mark Twain National Forest, Little Black River, and the beautiful Current River are also located in Ripley County.